Anal Sac Disease in Cats The anal sacs are two small pouches located on either side of the anus at approximately the four o'clock and eight o'clock positions. The walls of the sac are lined with a large number of sebaceous (sweat) glands that produce a foul smelling fluid.
The anal glands are one of the anatomical areas where cats have it all over dogs. Its unusual for a cats anal glands to become impacted, inflamed or infected, although some cats have overactive anal glands.
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It is not very common for cats to have recurrent anal sac disease, though some cats do (especially if they are overweight). The anal sacs of obese cats do not drain well, thus these cats are predisposed to recurrent problems.